Supplements & Nutraceuticals
Vitamins, minerals, botanical extracts, and nutraceutical compounds with clinical evidence for longevity, energy, cognition, and metabolic health.
Creatine
Creatine Monohydrate
The most studied sports supplement in history, now recognized for cognitive and longevity benefits beyond muscle performance. Safe, cheap, and effective.
Vitamin D3 + K2
Vitamin D3 with Vitamin K2 (MK-7)
The most important foundational supplement stack. Vitamin D3 is critical for immune function, bone health, and mood, while K2 directs calcium to bones and away from arteries.
Omega-3
Omega-3 Fatty Acids (EPA/DHA)
Essential fatty acids critical for brain health, cardiovascular function, and inflammation regulation. One of the most studied and recommended supplements globally.
Magnesium
Magnesium (Glycinate/Threonate/Citrate)
The most universally recommended supplement in the longevity community. Critical for 300+ enzymatic reactions, sleep quality, muscle function, and nervous system regulation.
CoQ10
Coenzyme Q10 (Ubiquinone/Ubiquinol)
An essential mitochondrial cofactor and potent antioxidant that declines with age. The landmark Q-SYMBIO trial demonstrated a 50% reduction in major cardiovascular events in heart failure patients. Widely used for energy, heart health, and statin side effect management.
Berberine
Berberine Hydrochloride
A bioactive alkaloid found in goldenseal, barberry, and Oregon grape with strong evidence for blood sugar control and cholesterol management. Often called 'nature's metformin' due to its AMPK-activating metabolic effects.
Resveratrol
Trans-Resveratrol
A polyphenol found in red grapes and wine that activates SIRT1 longevity pathways. The Baur et al. 2006 Nature study sparked global interest, though poor oral bioavailability (~1%) limits human translation of the compelling animal data.
Functional Mushrooms
Lion's Mane, Reishi, Cordyceps, Chaga
Medicinal mushroom extracts used for cognitive enhancement (Lion's Mane), immune support (Reishi), energy (Cordyceps), and antioxidant protection (Chaga).
Quercetin + Fisetin
Quercetin & Fisetin (Senolytic Stack)
A natural senolytic combination that selectively clears senescent 'zombie' cells. Kirkland's Mayo Clinic research established quercetin as a senolytic, while Yousefzadeh showed fisetin extends lifespan ~10% in mice. First-in-human pilot data is promising.
Astaxanthin
Astaxanthin (Carotenoid Antioxidant)
A potent carotenoid antioxidant derived from microalgae. 6000x stronger than vitamin C as an antioxidant. Supports skin, eye, and cardiovascular health.
NAD+ (Oral NMN/NR)
NMN/NR Oral Supplementation
Oral NAD+ precursors (NMN or NR) that boost cellular NAD+ levels. More accessible and affordable than injectable NAD+, though bioavailability is lower.
Spermidine
Spermidine (Polyamine)
A natural polyamine found in wheat germ that activates autophagy โ the body's cellular cleanup process. Emerging as a key longevity compound.
Methylene Blue
Pharmaceutical Grade Methylene Blue
A mitochondrial electron carrier and monoamine oxidase inhibitor with cognitive-enhancing and neuroprotective properties. Used at micro-doses for brain health.