NAC
N-Acetylcysteine
A powerful glutathione precursor and mucolytic agent used clinically for liver protection, respiratory health, and as an antidote for acetaminophen toxicity. Widely adopted in the longevity community for its antioxidant, anti-inflammatory, and detoxification properties.
How NAC Works
NAC is deacetylated to L-cysteine, the rate-limiting amino acid for glutathione synthesis. It also directly scavenges free radicals, modulates glutamate neurotransmission, and chelates heavy metals.
📊 Evidence by Outcome
Reliably raises glutathione levels by 30-50% within weeks. Clinical gold standard for glutathione repletion.
30 studies • Consistency: High • Effect: Large
FDA-approved antidote for acetaminophen toxicity. Protects against liver damage from various toxins and medications.
25 studies • Consistency: High • Effect: Large
Reduces mucus viscosity, improves COPD symptoms, and may reduce frequency of respiratory infections.
15 studies • Consistency: Moderate • Effect: Moderate
Key Research
Peer-Reviewed Evidence • 1 Citations
N-Acetylcysteine — a safe antidote for cysteine/glutathione deficiency
Atkuri KR et al.•Current Opinion in Pharmacology•2007•PMID: 17602868
Key Finding: Comprehensive review confirming NAC safely and reliably raises glutathione levels with broad therapeutic applications across liver disease, respiratory conditions, and psychiatric disorders.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Cost Guide
AED 50-150/month
Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.
Where to Get It (UAE)
Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.