NAC
Supplements & Nutraceuticals

NAC

N-Acetylcysteine

A powerful glutathione precursor and mucolytic agent used clinically for liver protection, respiratory health, and as an antidote for acetaminophen toxicity. Widely adopted in the longevity community for its antioxidant, anti-inflammatory, and detoxification properties.

100+ Studies140+ ReportsStrongOral + IVAvailable in UAE
80
Kamura ScoreStrong
80/100
Strong
Strong
Evidence
2-4 weeks
Time to Effect
AED 50-150/month
Est. Cost
Available
UAE Access
Last reviewed: March 2025
82
Research
80
Community
78
Safety
85
Access
82
Value

How NAC Works

NAC is deacetylated to L-cysteine, the rate-limiting amino acid for glutathione synthesis. It also directly scavenges free radicals, modulates glutamate neurotransmission, and chelates heavy metals.

📊 Evidence by Outcome

Glutathione ElevationA

Reliably raises glutathione levels by 30-50% within weeks. Clinical gold standard for glutathione repletion.

30 studies • Consistency: High • Effect: Large

Liver ProtectionA

FDA-approved antidote for acetaminophen toxicity. Protects against liver damage from various toxins and medications.

25 studies • Consistency: High • Effect: Large

Respiratory HealthB

Reduces mucus viscosity, improves COPD symptoms, and may reduce frequency of respiratory infections.

15 studies • Consistency: Moderate • Effect: Moderate

📄

Key Research

Peer-Reviewed Evidence • 1 Citations

[1]

N-Acetylcysteine — a safe antidote for cysteine/glutathione deficiency

Atkuri KR et al.Current Opinion in Pharmacology2007PMID: 17602868

Key Finding: Comprehensive review confirming NAC safely and reliably raises glutathione levels with broad therapeutic applications across liver disease, respiratory conditions, and psychiatric disorders.

View on PubMed

Citations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.

📋 Protocol Snapshot

Standard
600-1200mg daily
Take on empty stomach for best absorption. Can split into AM/PM doses.
Detox Support
1200-1800mg daily
Higher doses for active detoxification or post-alcohol support.

Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.

Cost Guide

AED 50-150/month

Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.

Where to Get It (UAE)

Browse all wellness centers →

Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.