GlyNAC
Glycine + N-Acetylcysteine (GlyNAC)
A combination of glycine and N-acetylcysteine that replenishes glutathione — the body's master antioxidant. Baylor College clinical trials showed GlyNAC supplementation reversed multiple hallmarks of aging in older adults and extended lifespan 24% in mice.
How GlyNAC Works
Glycine and NAC are the two rate-limiting precursors for glutathione synthesis. Supplementing both overcomes the age-related decline in glutathione, restoring the body's primary antioxidant defense system and supporting cellular detoxification, mitochondrial function, and immune health.
📊 Evidence by Outcome
Baylor RCT: 16 weeks of GlyNAC restored glutathione levels to those of young adults in participants aged 61-80.
5 studies • Consistency: High • Effect: Large
Improved mitochondrial function, reduced oxidative stress, inflammation, insulin resistance, genomic damage, and cellular senescence in older adults.
3 studies • Consistency: High • Effect: Large
Significant improvement in cognitive scores and processing speed in supplemented older adults vs. placebo.
3 studies • Consistency: Moderate • Effect: Moderate
Key Research
Peer-Reviewed Evidence • 1 Citations
Glycine and N-acetylcysteine supplementation corrects glutathione deficiency and reverses hallmarks of aging
Kumar P et al.•Clinical and Translational Medicine•2023•PMID: 36650097
Key Finding: 16-week RCT in older adults: GlyNAC corrected glutathione deficiency and improved/reversed oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genomic damage, cognition, strength, and gait speed.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Cost Guide
AED 100-250/month
Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.
Where to Get It (UAE)
Related Treatments
Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.