Lion's Mane
Lion's Mane Mushroom (Hericium erinaceus)
The premier nootropic mushroom, uniquely proven to stimulate Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF) production. Research supports its use for cognitive enhancement, neuroprotection, and nerve regeneration.
How Lion's Mane Works
Hericenones (from fruiting body) and erinacines (from mycelium) cross the blood-brain barrier and stimulate NGF and BDNF synthesis. This promotes neurogenesis, myelination, and synaptic plasticity — the biological basis for learning, memory, and nerve repair.
📊 Evidence by Outcome
Improved cognitive function scores in older adults with mild cognitive impairment after 16 weeks. Effects reversed after discontinuation.
8 studies • Consistency: Moderate • Effect: Moderate
Hericenones and erinacines uniquely stimulate NGF synthesis. The only known natural compound to cross the blood-brain barrier and promote nerve growth factor.
12 studies • Consistency: High • Effect: Large
Reduced depression and anxiety scores in clinical trials. Mechanism linked to NGF-mediated hippocampal neurogenesis.
5 studies • Consistency: Moderate • Effect: Moderate
Key Research
Peer-Reviewed Evidence • 1 Citations
Improving effects of the mushroom Yamabushitake on mild cognitive impairment
Mori K et al.•Phytotherapy Research•2009•PMID: 18844328
Key Finding: 3g/day Lion's Mane for 16 weeks significantly improved cognitive function in adults with mild cognitive impairment. Benefits reversed 4 weeks after discontinuation.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Cost Guide
AED 80-200/month
Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.
Where to Get It (UAE)
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Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.