Ashwagandha
Ashwagandha (Withania somnifera)
The most clinically validated adaptogen. Ashwagandha has strong evidence for reducing cortisol, improving stress tolerance, enhancing sleep quality, boosting testosterone, and supporting thyroid function. Used for over 3,000 years in Ayurvedic medicine.
How Ashwagandha Works
Ashwagandha's withanolides modulate the HPA axis, reducing cortisol production. It also enhances GABAergic signaling (promoting calm), supports thyroid hormone conversion, and acts as an antioxidant and anti-inflammatory.
📊 Evidence by Outcome
Multiple RCTs show 23-30% reduction in cortisol levels. Meta-analysis confirms significant stress and anxiety reduction.
15 studies • Consistency: High • Effect: Large
Systematic review: significantly improved sleep quality, sleep onset latency, and sleep efficiency. Particularly effective in those with insomnia.
10 studies • Consistency: High • Effect: Moderate
14-22% increase in testosterone in stressed males. Also improves sperm quality and fertility markers.
8 studies • Consistency: Moderate • Effect: Moderate
Normalized TSH and T4 levels in subclinical hypothyroidism patients. Use with caution in hyperthyroid conditions.
5 studies • Consistency: Moderate • Effect: Moderate
Key Research
Peer-Reviewed Evidence • 1 Citations
An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract
Salve J et al.•Medicine•2019•PMID: 31517876
Key Finding: 600mg/day KSM-66 for 8 weeks significantly reduced perceived stress (-44%), cortisol (-23%), and improved sleep quality vs. placebo in stressed adults.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
Side Effects & Safety
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Cost Guide
AED 50-150/month
Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.
Where to Get It (UAE)
Related Treatments
Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.