SS-31
Elamipretide / SS-31
A mitochondria-targeted peptide that stabilizes cardiolipin and restores electron transport chain function. Investigated for age-related mitochondrial dysfunction.
Key Research
Peer-Reviewed Evidence • 3 Citations
SS-31 peptide reverses the mitochondrial dysfunction and improves cardiac function in aged mice
Dai DF et al.•J Am Coll Cardiol•2011•PMID: 21636032
Key Finding: SS-31 reverses age-related mitochondrial dysfunction in cardiac tissue, restoring mitochondrial energetics comparable to young hearts.
View on PubMedElamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment in Alzheimer's disease models
Reddy PH et al.•J Alzheimers Dis•2018•PMID: 30149452
Key Finding: SS-31 reduces oxidative damage and improves synaptic function in Alzheimer's disease models, showing neuroprotective promise.
View on PubMedMitochondria-targeted peptide SS-31 ameliorates renal injury via reducing inflammation and oxidative stress
Liu D et al.•Oxid Med Cell Longev•2019•PMID: 31949881
Key Finding: SS-31 protects kidneys from ischemia-reperfusion injury by targeting the inner mitochondrial membrane and reducing ROS production.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📊 Evidence by Outcome
Targets inner mitochondrial membrane. Strong preclinical evidence for restoring mitochondrial function in aged tissues.
14 studies • Consistency: Moderate • Effect: Moderate
👥 Community Insights
Subtle increase in energy. Interesting compound but hard to access.
Community member • Europe• Verified
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Where to Get It (UAE)
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Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.