Longevity Protocols

The world's most popular longevity protocols — every supplement, exercise routine, diet, and practice detailed and compared.

6 protocolsContinuously updated

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Performance

Daily output

Anti-Aging

Slow biomarkers

Blueprint Protocol
Expert

Blueprint Protocol

by Bryan Johnson

The world's most measured human. A comprehensive anti-aging protocol backed by 100+ biomarkers and $2M+/year in testing.

$1,500-2,000+ (supplements & testing)3-4 hours/day22 supplements
longevityanti-agingbiohackingextreme
Outlive Protocol (Medicine 3.0)
Intermediate

Outlive Protocol (Medicine 3.0)

by Peter Attia

Proactive Medicine 3.0 — defeat the Four Horsemen of chronic disease through exercise, nutrition, sleep, emotional health, and targeted pharmacology.

$200-800 (supplements + periodic testing)10-14 hours/week (mostly exercise)9 supplements
longevitymedicine-3.0evidence-basedexercise
Huberman Lab Toolkit
Beginner

Huberman Lab Toolkit

by Andrew Huberman

Neuroscience-backed daily protocols for sleep, focus, energy, and performance — the most actionable wellness toolkit online.

$100-300 (supplements + sunlight is free)2-3 hours/day13 supplements
neurosciencecircadiandopaminesleep
Sinclair Longevity Protocol
Intermediate

Sinclair Longevity Protocol

by David Sinclair

The Information Theory of Aging — NMN, resveratrol, and lifestyle interventions to reprogram your epigenetic clock.

$200-500 (NMN + resveratrol are the main costs)1-2 hours/day10 supplements
longevityepigeneticsNMNsirtuins
Longevity Diet & FMD Protocol
Beginner

Longevity Diet & FMD Protocol

by Valter Longo

Fasting-mimicking science meets Blue Zone wisdom — the most researched dietary approach to longevity.

$50-250 (ProLon kit: ~$200 per 5-day cycle)Minimal daily (5-day FMD every 1-3 months)4 supplements
longevityfastingFMDBlue-Zones
FoundMyFitness Protocol
Intermediate

FoundMyFitness Protocol

by Rhonda Patrick

Micronutrient optimization and heat/cold stress — a research-dense, practical approach to healthspan based on nutrigenomics.

$150-400 (supplements + sauna access)1-2 hours/day9 supplements
micronutrientssaunasulforaphaneomega-3

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