Ketogenic Diet
A very low-carbohydrate, high-fat diet that shifts metabolism to produce ketone bodies for fuel. Originally developed for epilepsy, now researched for brain health, metabolic syndrome, cancer adjunct therapy, and weight management.
How Ketogenic Diet Works
Severe carbohydrate restriction depletes liver glycogen, forcing the liver to convert fatty acids into ketone bodies (BHB, AcAc, acetone). Ketones serve as an efficient alternative fuel for the brain and muscles, while reducing insulin levels and activating AMPK/autophagy pathways.
📊 Evidence by Outcome
Effective for rapid weight loss in the short-to-medium term. Meta-analyses show greater weight loss than low-fat diets at 6 months; difference narrows at 12 months.
40 studies • Consistency: High • Effect: Large (short-term)
The original medical application. 50%+ seizure reduction in ~50% of drug-resistant epilepsy patients.
30 studies • Consistency: High • Effect: Large
Ketones provide an alternative brain fuel. Emerging evidence for Alzheimer's, Parkinson's, and traumatic brain injury.
15 studies • Consistency: Moderate • Effect: Moderate
Key Research
Peer-Reviewed Evidence • 1 Citations
Dietary ketosis enhances memory in mild cognitive impairment
Krikorian R et al.•Neurobiology of Aging•2012•PMID: 21130529
Key Finding: 6-week very low-carb diet improved verbal memory performance in older adults with mild cognitive impairment, correlated with ketone levels.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Cost Guide
Variable (food costs)
Estimated UAE pricing. Costs vary by provider, dosage, and treatment plan.
Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.