Semax
Peptides

Semax

Semax Heptapeptide

A synthetic peptide analog of ACTH(4-7) developed in Russia for cognitive enhancement, neuroprotection, and stroke recovery. Promotes BDNF and NGF expression.

22+ Studies30+ ReportsEmergingNasal + Injectable
58
Kamura ScorePromising
55
Research
58
Community
78
Safety
40
Access
50
Value
📄

Key Research

Peer-Reviewed Evidence • 3 Citations

[1]

Semax (ACTH 4-10 analog) prevents oxidative damage of brain proteins and lipids following ischemia

Bashkatova VG et al.Eur J Pharmacol2001PMID: 11404082

Key Finding: Semax provides significant neuroprotection against ischemic brain injury by reducing oxidative stress markers and preserving brain tissue.

View on PubMed
[2]

Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems

Eremin KO et al.Neurochem Res2005PMID: 16258694

Key Finding: Semax activates dopamine and serotonin pathways, enhancing attention, memory formation, and learning in preclinical models.

View on PubMed
[3]

Neuroprotective and nootropic drug semax inhibits the expression of proinflammatory cytokines after focal cerebral ischemia

Medvedeva EV et al.Mol Biol (Mosk)2014PMID: 25508239

Key Finding: Semax suppresses pro-inflammatory gene expression after stroke, reducing brain inflammation and improving neurological recovery.

View on PubMed

Citations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.

📊 Evidence by Outcome

Cognitive EnhancementB

Enhances BDNF expression and cognitive performance. Approved in Russia for cerebrovascular disorders.

14 studies • Consistency: Moderate • Effect: Moderate

NeuroprotectionC

Used in stroke recovery protocols in Russia. Limited Western clinical data.

8 studies • Consistency: Mixed • Effect: Unclear

👥 Community Insights

30+
Reports
58%
Positive
3.5/5
Satisfaction
30 min - 1 hour
Time to Effect

Improved focus and verbal fluency. Subtle but noticeable.

Community memberDubai• Verified

📋 Protocol Snapshot

Nasal Spray
200-600mcg daily
Intranasal administration. Start low, titrate up.

Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.

Where to Get It (UAE)

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Related Treatments

Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.