Prolotherapy
Prolotherapy (Dextrose Injection Therapy)
Injection of dextrose (sugar water) solution into damaged joints, tendons, and ligaments to stimulate the body's natural healing response. Decades of use in sports medicine with growing RCT evidence for knee and low back pain.
Key Research
Peer-Reviewed Evidence • 2 Citations
Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial
Rabago D et al.•Ann Fam Med•2013•PMID: 23420128
Key Finding: RCT showed dextrose prolotherapy significantly improved pain and function in knee OA at 52 weeks vs saline injection.
View on PubMedA systematic review of dextrose prolotherapy for chronic musculoskeletal pain
Rabago D et al.•Clin J Sport Med•2005•PMID: 15782048
Key Finding: Systematic review found prolotherapy effective for chronic low back pain and knee OA in most controlled trials.
View on PubMedCitations sourced from PubMed, Cochrane Library, and peer-reviewed journals. Study findings are summarized for accessibility. Always consult the original publication for full methodology and results.
📊 Evidence by Outcome
Rabago et al. RCTs show significant pain and function improvement in knee OA at 12 months vs saline injection.
8 studies • Consistency: Moderate • Effect: Moderate
Mixed evidence for chronic low back pain. Some RCTs positive, others show no benefit over saline controls.
6 studies • Consistency: Mixed • Effect: Small
👥 Community Insights
After 4 prolotherapy sessions, my runner's knee finally stopped clicking. Back to training.
Community member • Dubai• Verified
📋 Protocol Snapshot
Protocols are for informational purposes only. Always consult a qualified healthcare provider before starting any treatment protocol.
Where to Get It (UAE)
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Medical Disclaimer: The information on this page is for educational purposes only and is not intended as medical advice. Kamura Scores reflect a combination of research evidence, community data, and other factors — they are not clinical recommendations. Research citations are provided for reference; always consult the original publications for complete study details. Consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Individual results may vary.